Unipolar Depression

Unipolar Depression (Major Depressive Disorder) is a mood disorder characterized by a persistently low mood and loss of interest in activities, without the manic or hypomanic episodes that characterize bipolar disorders.

Key Points:

• Symptoms: Sadness, anhedonia, fatigue, changes in sleep/appetite, feelings of worthlessness, difficulty concentrating, possible suicidal ideation.
• Distinction from Bipolar Disorder: Unipolar depression does not include mania or hypomania.
• Treatment: Antidepressants (SSRIs, SNRIs), psychotherapy (CBT, interpersonal therapy), lifestyle modifications, and support systems.