Wernicke’s Encephalopathy

Last reviewed Thursday, January 09, 2025

Wernicke’s Encephalopathy is an acute neurological condition caused by severe thiamine (vitamin B1) deficiency, often associated with chronic alcoholism. It’s characterized by confusion, oculomotor dysfunction, and ataxia.

Key Points:

  • Symptoms (Classic Triad): Confusion, eye movement abnormalities (nystagmus, ophthalmoplegia), unsteady gait.
  • Progression: If untreated, can lead to Korsakoff Syndrome (persistent memory problems) or death.
  • Treatment: Immediate administration of thiamine; nutritional support; addressing alcohol misuse.
  • Prevention: Adequate diet, monitoring thiamine levels in high-risk populations.

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