Zolpidem

Last reviewed Monday, January 27, 2025

Zolpidem (Ambien) is a prescription sedative-hypnotic (a “Z-drug”) commonly used to treat insomnia. It targets certain GABA receptors in the brain to induce sleep.

Key Points:

  • Duration: Short-acting, primarily helpful for initiating sleep.
  • Side Effects: Drowsiness, dizziness, risk of dependence, and rare behaviors like sleepwalking or sleep-eating.
  • Guidelines: Best used at the lowest effective dose for the shortest necessary period to reduce dependence.
  • Alternatives: Lifestyle modifications, CBT for insomnia, other non-drug interventions.

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