Zopiclone

Last reviewed Wednesday, January 29, 2025

Zopiclone (brand names vary by country) is another non-benzodiazepine hypnotic agent in the “Z-drug” class, used for short-term management of insomnia.

Key Points:

  • Mechanism: Enhances GABA receptor function, promoting sedation.
  • Side Effects: Bitter or metallic taste, dry mouth, risk of dependence if used long-term.
  • Usage: Typically prescribed for short treatment periods (1–4 weeks) to restore normal sleep patterns.
  • Caution: Avoid mixing with alcohol; monitor for daytime sedation or rebound insomnia upon discontinuation.

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